WARNING: NEPHROTOXICITY, PERIPHERAL NEUROPATHY, NAUSEA AND VOMITING, and MYELOSUPPRESSION
See full prescribing information for complete boxed warning.

• Nephrotoxicity: cisplatin for injection can cause severe renal toxicity, including acute renal failure. Ensure adequate hydration. Consider dose reductions or alternative treatments in patients with renal impairment.
• Peripheral Neuropathy: cisplatin for injection can cause dose-related peripheral neuropathy.
• Nausea and Vomiting: cisplatin for injection can cause severe nausea and vomiting. Premedicate with antiemetics.
• Myelosuppression: cisplatin for injection can cause severe myelosuppression with fatalities due to infections. Monitor blood counts and interrupt therapy accordingly.